Wednesday 19 December 2012

New immune therapy successfully treats brain tumors in mice

Using an artificial protein that stimulates the body’s natural immune system to fight cancer, a research team at Duke Medicine has engineered a lethal weapon that kills brain tumors in mice while sparing other tissue. If it can be shown to work in humans, it would overcome a major obstacle that has hampered the effectiveness of immune-based therapies. In six out of eight mice with brain tumors, the treatment resulted in cures, according to findings published in the Proceedings of the National Academy of Sciences. Read more here.

Study mentioned: Choi BD, et al. Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma. Proc Natl Acad Sci U S A. 2012 Dec 17. [Epub ahead of print] PMID: 23248284

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