Tuesday 4 December 2012

Lung cancer patients developing areas of drug-resistance prolong disease control by using focused radiation to weed the garden

A University of Colorado Cancer Center study published in the Journal of Thoracic Oncology shows that when pockets of resistant cancer develop, it’s often possible to zap these resistant pockets with focused, targeted radiation while continuing crizotinib or erlotinib to maintain control of the majority of the disease that continues to depend on the primary mutation. Read more here.

Study mentioned: Weickhardt AJ, et al. Local ablative therapy of oligoprogressive disease prolongs disease control by tyrosine kinase inhibitors in oncogene-addicted non-small-cell lung cancer. J Thorac Oncol. 2012 Dec;7(12):1807-14. PMID: 23154552

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