A research team led by scientists at Mayo Clinic in Florida have decoded the entire pathway that regulates leakiness of blood vessels — a condition that promotes a wide number of disorders, such as heart disease, cancer growth and spread, inflammation and respiratory distress. They say their findings, published online in the Journal of Cell Biology, suggest that several agents already being tested for other conditions might reverse vessel leakiness. Read more here.
Study mentioned: Ngok SP, et al. VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. J Cell Biol. Published December 17, 2012.
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