St. Jude Children’s Research Hospital scientists have discovered a way to target the immune system to shrink or eliminate tumors in mice without causing autoimmune problems. Researchers also found evidence that the same mechanism may operate in humans. The findings provide a new target for ongoing efforts to develop immunotherapies to harness the immune system to fight cancer and other diseases. Read more here.
Study mentioned: Delgoffe GM, et al. Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. Nature. 2013 Aug 4. doi: 10.1038/nature12428. [Epub ahead of print] PMID: 23913274
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