Wednesday, 14 August 2013

Scientists use genome sequencing to prove herbal remedy causes upper urinary tract cancers

Genomic sequencing experts at Johns Hopkins partnered with pharmacologists at Stony Brook University to reveal a striking mutational signature of upper urinary tract cancers caused by aristolochic acid, a plant compound contained in herbal remedies used for thousands of years to treat a variety of ailments such as arthritis, gout and inflammation. Read more here.

Study mentioned: Hoang ML, et al. Mutational signature of aristolochic Acid exposure as revealed by whole-exome sequencing. Sci Transl Med. 2013 Aug 7;5(197):197ra102. PMID: 23926200

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