In the Journal of Clinical Investigation, Catherine Wu and colleagues at the Dana Farber Cancer Institute in Boston report the results of a clinical trial that tested the effectiveness of vaccination with a CLL patient's own leukemia cells in the development of anti-tumor responses and relapse reduction. Patients with advanced CLL were vaccinated with their own irradiated tumor cells following allo-HSCT. Nearly 3 years after vaccination, 13 of the 18 vaccinated patients were in complete remission. Read more here.
Study mentioned: Burkhardt UE, et al. Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells. J Clin Invest. 2013 Aug 5. [Epub ahead of print] PMID: 23912587
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