Tuesday 5 November 2013

Fewer doses of HPV vaccine result in immune response similar to three-dose regimen

NCI scientists report that two doses of a human papillomavirus (HPV) vaccine, trademarked as Cervarix, resulted in similar serum antibody levels against two of the most carcinogenic types of HPV (16 and 18), compared to a standard three dose regimen. Among women who received only one dose, antibody levels were also high and remained stable four years after vaccination. The results suggest that fewer doses of an HPV vaccine may confer necessary long-term protection against new infection and appeared in Cancer Prevention Research. Read more here.

Study mentioned: Safaeian M, et al. Durable Antibody Responses Following One Dose of the Bivalent Human Papillomavirus L1 Virus-Like Particle Vaccine in the Costa Rica Vaccine Trial. Cancer Prev Res. November 2013;6:1242.

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