Thursday, 28 November 2013

Two human proteins found to affect how "jumping gene" gets around

Using a new method to catch elusive “jumping genes” in the act, researchers have found two human proteins that are used by one type of DNA to replicate itself and move from place to place. The discovery breaks new ground, they say, in understanding the arms race between a jumping gene driven to colonize new areas of the human genome and cells working to limit the risk posed by such volatile bits of DNA. Read more here.

Study mentioned: Taylor MS, et al. Affinity Proteomics Reveals Human Host Factors Implicated in Discrete Stages of LINE-1 Retrotransposition. Cell. 2013 Nov 21;155(5):1034-48. PMID: 24267889

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