Monday 18 March 2013

USC researchers show increase of cell mutations with age

Like an old car that gradually rusts as it ages, even if there is no lethal damage to a critical part of the car, a human body accumulates genetic damage as it becomes older. For the first time, research at the Keck School of Medicine of USC showed evidence that cell mutations increase with age, causing supposedly identical cells to diverge genetically. The report is featured in the journal Aging Cell. Read more here.

Study mentioned: Hsieh JC, et al. Large chromosome deletions, duplications, and gene conversion events accumulate with age in normal human colon crypts. Aging Cell. 2013 Feb 20. [Epub ahead of print] PMID: 23425690

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