Friday, 28 June 2013

BRAF-mutated colon cancer may be less responsive to aspirin's positive effects

Compiling results of two large studies, researchers have identified biomarkers of response to aspirin among those taking the oral drug either as a way to treat or prevent colorectal cancer. The analysis shows that the effect of aspirin on colorectal cancer depends on whether or not the cancer harbors a BRAF mutation: those cancers that were BRAF mutated were less sensitive to aspirin. Read more here.

Study mentioned: Nishihara R, et al. Aspirin Use and Risk of Colorectal Cancer According to BRAF Mutation Status. JAMA. 2013 Jun 26;309(24):2563-71. PMID: 23800934

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