Monday, 10 June 2013

Tumors disable immune cells by using up sugar

Cancer cells’ appetite for sugar may have serious consequences for immune cell function, researchers at Washington University School of Medicine in St. Louis have learned. The scientists found that when they kept sugar away from critical immune cells called T cells, the cells no longer produced interferon gamma, an inflammatory compound important for fighting tumors and some kinds of infection. Read more here.

Study mentioned: Chang C, et al. (2013) Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis. Cell. 153(6):1239-1251.

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