Researchers and clinicians have been searching for a human-cell model of the early-disease progression of pancreatic cancer. Perelman School of Medicine, University of Pennsylvania scientists have used stem-cell technology to create a research cell line from a patient with advanced pancreatic ductal adenocarcinoma (PDAC). This first-of-its-kind human-cell model of pancreatic cancer progression was published in Cell Reports from the lab of Ken Zaret, PhD, professor of Cell and Developmental Biology. Read more here.
Study mentioned: Kim J, et al. An iPSC Line from Human Pancreatic Ductal Adenocarcinoma Undergoes Early to Invasive Stages of Pancreatic Cancer Progression. Cell Rep. 2013 Jun 19. pii: S2211-1247(13)00269-6. [Epub ahead of print] PMID: 23791528
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