Researchers at the University of California, San Diego School of Medicine, with colleagues at the University of Rochester Medical Center, have identified a new mechanism that appears to suppress tumor growth, opening the possibility of developing a new class of anti-cancer drugs. Willis X. Li, PhD, reports that a particular form of a signaling protein called STAT5A stabilizes the formation of heterochromatin, which in turn suppresses the ability of cancer cells to issue instructions to multiply and grow. Read more here.
Study mentioned: Hu X, et al. Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth. Proc Natl Acad Sci U S A. 2013 Jun 3. [Epub ahead of print] PMID: 23733954
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