Antiandrogens and hepatotoxicity

The October 2012 Canadian Adverse Reaction Newsletter includes a section on antiandrogens and hepatotoxicity. Antiandrogens are a class of drugs used in androgen deprivation therapy for the treatment of advanced or metastatic prostate cancer. They are classified into two groups. Both groups work by competing with circulating androgens for receptor sites within the prostate cell, thus promoting apoptosis and inhibiting prostate cancer growth. Read the newsletter here.