Wednesday 31 October 2012

Lactation protein suppresses tumors and metastasis in breast cancer

A protein that is necessary for lactation in mammals inhibits the critical cellular transition that is an early indicator of breast cancer and metastasis, according to research conducted at the University at Buffalo and Princeton University and highlighted as the cover paper in November issue of Nature Cell Biology. Read more here.

Study mentioned: Chakrabarti R, et al. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. Nat Cell Biol. 2012 Oct 21. [Epub ahead of print] PMID: 23086238

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