Doxorubicin remains the gold standard in the first line chemotherapy for patients with advanced or metastatic soft tissue sarcoma

The EORTC 62012 trial attempted to resolve controversy regarding whether ifosfamide had been previously tested at too low dose when used with doxorubicin by evaluating whether a higher dose of ifosfamide plus doxorubicin could improve response rate and progression free survival (PFS) in patients with locally advanced or metastatic, grade 2 or 3 soft tissue sarcoma (STS). The results are presented by Dr Winette van der Graaf at the Presidential symposium of the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna. Read more here.