Targeting the cancer microenvironment

Dr Giuseppe Curigliano from the European Institute of Oncology, Milan, Italy, made the strong case for more research to be performed into cancer microenvironments. Cancer cells interact with normal host stromal cells (e.g. endothelial cells, fibroblasts, various immune cells) with a complex extracellular matrix secreted by both the normal and neoplastic cells embedded in it. Read more here.