Friday 18 January 2013

Body's ibuprofen, SPARC, reduces inflammation and thus bladder cancer development and metastasis

A University of Colorado Cancer Center study published in the Journal of Clinical Investigation shows that the protein SPARC (Secreted Protein Acidic and Rich in Cysteine) acts much like an anti-inflammatory drug, attempting to heal tissues inflamed by tumors. Likewise, cancers – for example, bladder cancer in this study – have developed ways to turn off the production of SPARC, thus allowing growth and metastasis, especially to the lung where bladder cancer is frequently fatal. Read more here.

Study mentioned: Said N, et al. Loss of SPARC in bladder cancer enhances carcinogenesis and progression. J Clin Invest. 2013 Jan 16. [Epub ahead of print] PMID: 23321672

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