Thursday, 31 January 2013

Preclinical study identifies 'master' proto-oncogene that regulates stress-induced ovarian cancer metastasis

Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins - known as Src - leads to ovarian cancer progression when exposed to stress hormones. The researchers report in the current issue of Nature Communications that beta blocker drugs mitigate this effect and reduce cancer deaths by an average of 17 percent. Read more here.

Study mentioned: Armaiz-Pena GN, et al. Src activation by β-adrenoreceptors is a key switch for tumour metastasis. Nat Commun. 2013 Jan 29;4:1403. PMID: 23360994

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