Wednesday 16 January 2013

Fox Chase researchers discover novel role of the NEDD9 gene in early stages of breast cancer

Researchers at Fox Chase Cancer Center have shown that NEDD9 plays a surprising role in the early stages of breast tumor development by controlling the growth of progenitor cells that give rise to tumors. The findings, published in the journal Oncogene, could lead to personalized treatment strategies for women with breast cancer based on the levels of NEDD9 in their tumors. Read more here.

Study mentioned: Little JL, et al. A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice. Oncogene. 2013 Jan 14. [Epub ahead of print] PMID: 23318423

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