Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many pancreatic and prostate tumors, according to research at the National Institutes of Health. Read more here.
Study mentioned: Kohaar I, et al. Genetic Variant as a Selection Marker for Anti-Prostate Stem Cell Antigen Immunotherapy of Bladder Cancer. J Natl Cancer Inst. 2012 Dec 23. [Epub ahead of print] PMID: 23266392
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